PDLIM7 antibody (AA 275-457) (Fluoro594)

Catalog No. ABIN8019954

The Rabbit Polyclonal anti-PDLIM7 antibody is suitable to detect PDLIM7 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for PDLIM7 antibody (AA 275-457) (Fluoro594) (ABIN8019954)

Target: PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDLIM7 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-PDLIM7 Antibody (Fluoro594)

Binding Specificity: AA 275-457

Purpose: Anti-PDLIM7 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PDLIM7 recombinant protein (Position: N275-V457).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PDLIM7

Target: PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

Alternative Name: PDLIM7

Background:

Background: PDZ and LIM domain protein 7 is a protein that in humans is encoded by the PDLIM7 gene. The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: PDZ and LIM domain 7

Gene ID: 9260

UniProt: Q9NR12