Pellino 1 antibody (N-Term) (Fluoro647)

Catalog No. ABIN8020004

This Rabbit Polyclonal antibody specifically detects Pellino 1 in WB, IHC, IP and FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Pellino 1 antibody (N-Term) (Fluoro647) (ABIN8020004)

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pellino 1 antibody is conjugated to Fluoro647

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Product Details anti-Pellino 1 Antibody (Fluoro647)

Binding Specificity: N-Term

Purpose: Anti-PELI1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PELI1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human, Rat

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Pellino 1

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Alternative Name: PELI1

Background:

Background: Enables ubiquitin-ubiquitin ligase activity. Involved in several processes, including negative regulation of TORC1 signaling, negative regulation of necroptotic process, and protein polyubiquitination. Is active in site of double-strand break. Implicated in colorectal cancer.

Gene Full Name: pellino E3 ubiquitin protein ligase 1

Gene ID: 57162

UniProt: Q96FA3

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades