PGLYRP1 antibody (C-Term) (Biotin)

Catalog No. ABIN8020184

This Rabbit Polyclonal antibody specifically detects PGLYRP1 in WB, IHC and ELISA. It exhibits reactivity toward Mouse and Rat.

Quick Overview for PGLYRP1 antibody (C-Term) (Biotin) (ABIN8020184)

Target: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGLYRP1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PGLYRP1 Antibody (Biotin)

Binding Specificity: C-Term

Purpose: Anti-PGLYRP1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse PGLYRP1 shares 64.3%,80% amino acid (aa) sequence identity with human,rat PGLYRP1,respectively.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse PGLYRP1. Mouse PGLYRP1 shares 64.3% and 80% amino acid (aa) sequence identity with human and rat PGLYRP1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PGLYRP1

Target: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Alternative Name: PGLYRP1

Background:

Background: Predicted to enable several functions, including Hsp70 protein binding activity, peptidoglycan binding activity, and peptidoglycan immune receptor activity. Acts upstream of or within several processes, including negative regulation of inflammatory response, negative regulation of natural killer cell differentiation involved in immune response, and negative regulation of type II interferon production. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Is expressed in alimentary system, craniocervical region bone, genitourinary system, liver, and respiratory system. Orthologous to human PGLYRP1 (peptidoglycan recognition protein 1).

Gene Full Name: peptidoglycan recognition protein 1

Gene ID: 21946

UniProt: O88593

Pathways: Activation of Innate immune Response