PEX14 antibody (N-Term) (PE)

Catalog No. ABIN8020746

The Rabbit Polyclonal anti-PEX14 antibody is suitable to detect PEX14 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for PEX14 antibody (N-Term) (PE) (ABIN8020746)

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX14 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-PEX14 Antibody (PE)

Binding Specificity: N-Term

Purpose: Anti-PEX14 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PEX14 shares 95.8% amino acid (aa) sequence identity with both mouse,rat PEX14.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PEX14. Human PEX14 shares 95.8% amino acid (aa) sequence identity with both mouse and rat PEX14.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PEX14

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Alternative Name: PEX14

Background:

Background: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

Gene Full Name: peroxisomal biogenesis factor 14

Gene ID: 5195

UniProt: O75381

Pathways: Maintenance of Protein Location