PEX19 antibody (AA 51-269)

Catalog No. ABIN8020771

The Rabbit Polyclonal anti-PEX19 antibody (ABIN8020771) specifically detects PEX19 in WB, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for PEX19 antibody (AA 51-269) (ABIN8020771)

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-PEX19 Antibody

Binding Specificity: AA 51-269

Purpose: Anti-PEX19 Antibody

Predicted Reactivity: Human PEX19 shares 91.8%,94.5% amino acid (aa) sequence identity with mouse,rat PEX19,respectively.

Characteristics: Anti-PEX19 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PEX19 recombinant protein (Position: Q51-A269). Human PEX19 shares 91.8% and 94.5% amino acid (aa) sequence identity with mouse and rat PEX19, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PEX19

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Alternative Name: PEX19

Background:

Background: Peroxisomal biogenesis factor 19 is a protein that in humans is encoded by the PEX19 gene. This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Gene Full Name: peroxisomal biogenesis factor 19

Molecular Weight: 38 kDa

Gene ID: 5824

UniProt: P40855