PHF15 antibody (AA 36-260) (Biotin)

Catalog No. ABIN8020952

This Rabbit Polyclonal antibody specifically detects PHF15 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for PHF15 antibody (AA 36-260) (Biotin) (ABIN8020952)

Target: PHF15 (PHD Finger Protein 15 (PHF15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF15 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PHF15 Antibody (Biotin)

Binding Specificity: AA 36-260

Purpose: Anti-PHF15/JADE2 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Mouse Cd14 shares 68.2%,85.7% amino acid (aa) sequence identity with human,rat CD14,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Cd14 recombinant protein (Position: D36-A260). Mouse Cd14 shares 68.2% and 85.7% amino acid (aa) sequence identity with human and rat CD14, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PHF15

Target: PHF15 (PHD Finger Protein 15 (PHF15))

Alternative Name: JADE2

Background:

Background: PHF15, also known as Protein Jade-2, has 3 isoforms, a 790 amino acid isoform that is 87 kDa, a 789 amino acid isoform that is 87 kDa and a 562 amino acid isoform that is 63 kDa, has a histone H4-specific acetyltransferase activity as a component of the HBO1complex, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. This protein has been shown an interaction with ING4, KAT7, ING5, PACSIN, ZBTB3, ZBTB5, ZNF496, and VHL proteins in histone H3 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, and histone H4-K12 acetylation biological processes.

Gene Full Name: jade family PHD finger 2

Gene ID: 23338

UniProt: Q9NQC1