PHEX antibody (AA 145-718) (Cy3)

Catalog No. ABIN8021178

The Rabbit Polyclonal anti-PHEX antibody is suitable to detect PHEX in samples from Human, Rat, Mouse and Monkey. It has been validated for FACS.

Quick Overview for PHEX antibody (AA 145-718) (Cy3) (ABIN8021178)

Target: PHEX (Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX))

Reactivity: Human, Rat, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHEX antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-PHEX Antibody (Cy3)

Binding Specificity: AA 145-718

Purpose: Anti-PHEX Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PHEX recombinant protein (Position: E145-N718).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PHEX

Target: PHEX (Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX))

Alternative Name: PHEX

Background:

Background: Phosphate-regulating neutral endopeptidase, X-linked also known as phosphate-regulating gene with homologies to endopeptidases on the X chromosome or metalloendopeptidase homolog PEX is an enzyme that in humans is encoded by the PHEX gene. It is mapped to Xp22.11. The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants.

Gene Full Name: phosphate regulating endopeptidase X-linked

Gene ID: 5251

UniProt: P78562