PHEX antibody (AA 145-718) (HRP)

Catalog No. ABIN8021183

This Rabbit Polyclonal antibody specifically detects PHEX in ELISA, WB and IHC. It exhibits reactivity toward Human, Rat, Mouse and Monkey.

Quick Overview for PHEX antibody (AA 145-718) (HRP) (ABIN8021183)

Target: PHEX (Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX))

Reactivity: Human, Rat, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHEX antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PHEX Antibody (HRP)

Binding Specificity: AA 145-718

Purpose: Anti-PHEX Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PHEX recombinant protein (Position: E145-N718).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PHEX

Target: PHEX (Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX))

Alternative Name: PHEX

Background:

Background: Phosphate-regulating neutral endopeptidase, X-linked also known as phosphate-regulating gene with homologies to endopeptidases on the X chromosome or metalloendopeptidase homolog PEX is an enzyme that in humans is encoded by the PHEX gene. It is mapped to Xp22.11. The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants.

Gene Full Name: phosphate regulating endopeptidase X-linked

Gene ID: 5251

UniProt: P78562