PDE4A antibody (N-Term)

Catalog No. ABIN8021422

The Rabbit Polyclonal anti-PDE4A antibody (ABIN8021422) specifically detects PDE4A in IHC and IF. The antibody is reactive with Human samples.

Quick Overview for PDE4A antibody (N-Term) (ABIN8021422)

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PDE4A Antibody

Binding Specificity: N-Term

Purpose: Anti-PDE4A Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PDE4A shares 100% amino acid (aa) sequence identity with both mouse,rat PDE4A.

Characteristics: Anti-PDE4A Antibody-1. Tested in IHC, IF applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PDE4A. Human PDE4A shares 100% amino acid (aa) sequence identity with both mouse and rat PDE4A.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PDE4A

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Alternative Name: PDE4A

Background:

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: phosphodiesterase 4A

Gene ID: 5141

UniProt: P27815

Pathways: cAMP Metabolic Process