PDE4A antibody (N-Term) (Fluoro550)

Catalog No. ABIN8021426

This Rabbit Polyclonal antibody specifically detects PDE4A in FACS. It exhibits reactivity toward Human.

Quick Overview for PDE4A antibody (N-Term) (Fluoro550) (ABIN8021426)

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4A antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-PDE4A Antibody (Fluoro550)

Binding Specificity: N-Term

Purpose: Anti-PDE4A Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PDE4A shares 100% amino acid (aa) sequence identity with both mouse,rat PDE4A.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PDE4A. Human PDE4A shares 100% amino acid (aa) sequence identity with both mouse and rat PDE4A.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PDE4A

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Alternative Name: PDE4A

Background:

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: phosphodiesterase 4A

Gene ID: 5141

UniProt: P27815

Pathways: cAMP Metabolic Process