PFKP antibody (AA 55-784) (PE)

Catalog No. ABIN8021633

This Rabbit Polyclonal antibody specifically detects PFKP in FACS. It exhibits reactivity toward Human.

Quick Overview for PFKP antibody (AA 55-784) (PE) (ABIN8021633)

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKP antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-PFKP Antibody (PE)

Binding Specificity: AA 55-784

Purpose: Anti-PFKP Antibody PE Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PFKP shares 90.1%,89.8% amino acid (aa) sequence identity with mouse,rat PFKP,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PFKP recombinant protein (Position: A55-V784). Human PFKP shares 90.1% and 89.8% amino acid (aa) sequence identity with mouse and rat PFKP, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PFKP

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Alternative Name: PFKP

Background:

Background: Phosphofructokinase, platelet, also known as PFKP is an enzyme which in humans is encoded by the PFKP gene. This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.

Gene Full Name: phosphofructokinase, platelet

Gene ID: 5214

UniProt: Q01813

Pathways: Warburg Effect