PFKP antibody (AA 55-784)

Catalog No. ABIN8021635

The Rabbit Polyclonal anti-PFKP antibody (ABIN8021635) specifically detects PFKP in WB, IHC, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for PFKP antibody (AA 55-784) (ABIN8021635)

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-PFKP Antibody

Binding Specificity: AA 55-784

Purpose: Anti-PFKP Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PFKP shares 90.1%,89.8% amino acid (aa) sequence identity with mouse,rat PFKP,respectively.

Characteristics: Anti-PFKP Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PFKP recombinant protein (Position: A55-V784). Human PFKP shares 90.1% and 89.8% amino acid (aa) sequence identity with mouse and rat PFKP, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PFKP

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Alternative Name: PFKP

Background:

Background: Phosphofructokinase, platelet, also known as PFKP is an enzyme which in humans is encoded by the PFKP gene. This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.

Gene Full Name: phosphofructokinase, platelet

Molecular Weight: 86 kDa

Gene ID: 5214

UniProt: Q01813

Pathways: Warburg Effect