PGD antibody (AA 24-447) (Biotin)

Catalog No. ABIN8021680

The Biotin-conjugated Rabbit Polyclonal anti-PGD antibody (ABIN8021680) specifically detects PGD in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PGD antibody (AA 24-447) (Biotin) (ABIN8021680)

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGD antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PGD Antibody (Biotin)

Binding Specificity: AA 24-447

Purpose: Anti-PGD Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PGD shares 93.9%,92.9% amino acid (aa) sequence identity with mouse,rat PGD,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PGD recombinant protein (Position: D24-R447). Human PGD shares 93.9% and 92.9% amino acid (aa) sequence identity with mouse and rat PGD, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PGD

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Alternative Name: PGD

Background:

Background: 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: phosphogluconate dehydrogenase

Gene ID: 5226

UniProt: P52209