PIK3C3 antibody (C-Term) (Biotin)

Catalog No. ABIN8021901

The Rabbit Polyclonal anti-PIK3C3 antibody is suitable to detect PIK3C3 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for PIK3C3 antibody (C-Term) (Biotin) (ABIN8021901)

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3C3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PIK3C3 Antibody (Biotin)

Binding Specificity: C-Term

Purpose: Anti-VPS34/PIK3C3 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human VPS34,PIK3C3 shares 100% amino acid (aa) sequence identity with both mouse,rat VPS34,PIK3C3.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human VPS34/PIK3C3. Human VPS34/PIK3C3 shares 100% amino acid (aa) sequence identity with both mouse and rat VPS34/PIK3C3.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PIK3C3

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Alternative Name: PIK3C3

Background:

Background: Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including early endosome to late endosome transport, macroautophagy, and phosphatidylinositol-3-phosphate biosynthetic process. Acts upstream of or within autophagy and positive regulation of protein lipidation. Located in autolysosome, late endosome, and midbody. Part of phosphatidylinositol 3-kinase complex, class III.

Gene Full Name: phosphatidylinositol 3-kinase catalytic subunit type 3

Gene ID: 5289

UniProt: Q8NEB9

Pathways: AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy