PLA2R1 antibody (AA 21-66) (Biotin)

Catalog No. ABIN8021978

This Rabbit Polyclonal antibody specifically detects PLA2R1 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for PLA2R1 antibody (AA 21-66) (Biotin) (ABIN8021978)

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2R1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PLA2R1 Antibody (Biotin)

Binding Specificity: AA 21-66

Purpose: Anti-PLA2R/PLA2R1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLA2R/PLA2R1 recombinant protein (Position: E21-Q66).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLA2R1

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Alternative Name: PLA2R1

Background:

Background: Secretory phospholipase A2 receptor is an enzyme that in humans is encoded by the PLA2R1 gene. This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: phospholipase A2 receptor 1

Gene ID: 22925

UniProt: Q13018

Pathways: Positive Regulation of Response to DNA Damage Stimulus