PLA2G3 antibody (AA 74-358)

Catalog No. ABIN8022011

This Rabbit Polyclonal antibody specifically detects PLA2G3 in WB, ELISA and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for PLA2G3 antibody (AA 74-358) (ABIN8022011)

Target: PLA2G3 (Phospholipase A2, Group III (PLA2G3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-PLA2G3 Antibody

Binding Specificity: AA 74-358

Purpose: Anti-PLA2G3 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PLA2G3 shares 66.8% amino acid (aa) sequence identity with mouse PLA2G3.

Characteristics: Anti-PLA2G3 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLA2G3 recombinant protein (Position: E74-R358). Human PLA2G3 shares 66.8% amino acid (aa) sequence identity with mouse PLA2G3.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLA2G3

Target: PLA2G3 (Phospholipase A2, Group III (PLA2G3))

Alternative Name: PLA2G3

Background:

Background: This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease.

Gene Full Name: phospholipase A2 group III

Molecular Weight: 65 kDa

Gene ID: 50487

UniProt: Q9NZ20