PLA2G4B antibody (AA 61-781) (Biotin)

Catalog No. ABIN8022034

The Biotin-conjugated Rabbit Polyclonal anti-PLA2G4B antibody (ABIN8022034) specifically detects PLA2G4B in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PLA2G4B antibody (AA 61-781) (Biotin) (ABIN8022034)

Target: PLA2G4B (Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G4B antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PLA2G4B Antibody (Biotin)

Binding Specificity: AA 61-781

Purpose: Anti-cPLA2 beta/PLA2G4B Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human cPLA2 beta/PLA2G4B recombinant protein (Position: N61-H781).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLA2G4B

Target: PLA2G4B (Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B))

Alternative Name: PLA2G4B

Background:

Background: Phospholipase A2, group IVB (cytosolic), also known as PLA2G4B, is a human gene. This gene encodes a member of the cytosolic phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of phospholipids, releasing lysophospholipids and fatty acids. This enzyme may be associated with mitochondria and early endosomes. Most tissues also express read-through transcripts from the upstream gene into this gene, some of which may encode fusion proteins combining the N-terminus of the upstream gene including its JmjC domain with the almost complete coding region of this gene, including the C2 and cytoplasmic phospholipase A2 domains.

Gene Full Name: phospholipase A2 group IVB

Gene ID: 100137049

UniProt: P0C869

Pathways: ER-Nucleus Signaling, VEGF Signaling