PLA2G15 antibody (AA 92-372) (Biotin)

Catalog No. ABIN8022080

This Rabbit Polyclonal antibody specifically detects PLA2G15 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for PLA2G15 antibody (AA 92-372) (Biotin) (ABIN8022080)

Target: PLA2G15 (Phospholipase A2, Group XV (PLA2G15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G15 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PLA2G15 Antibody (Biotin)

Binding Specificity: AA 92-372

Purpose: Anti-LYPLA3/PLA2G15 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LYPLA3/PLA2G15 recombinant protein (Position: D92-Q372).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLA2G15

Target: PLA2G15 (Phospholipase A2, Group XV (PLA2G15))

Alternative Name: PLA2G15

Background:

Background: LYPLA3, also known as Group XV phospholipase A2, is an enzyme that in humans is encoded by the PLA2G15 gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.

Gene Full Name: phospholipase A2 group XV

Gene ID: 23659

UniProt: Q8NCC3

Pathways: Monocarboxylic Acid Catabolic Process