Phospholipase C beta 2 antibody (AA 27-1185) (APC)

Catalog No. ABIN8022121

The APC-conjugated Rabbit Polyclonal anti-Phospholipase C beta 2 antibody (ABIN8022121) specifically detects Phospholipase C beta 2 in FACS. The antibody is reactive with Human samples.

Quick Overview for Phospholipase C beta 2 antibody (AA 27-1185) (APC) (ABIN8022121)

Target: Phospholipase C beta 2 (PLCb2) (phospholipase C beta 2 (PLCb2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C beta 2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Phospholipase C beta 2 Antibody (APC)

Binding Specificity: AA 27-1185

Purpose: Anti-PLCB2 Antibody APC Conjugated

Predicted Reactivity: Human PLCB2 shares 85.7%,85.3% amino acid (aa) sequence identity with mouse,rat PLCB2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLCB2 recombinant protein (Position: D27-L1185). Human PLCB2 shares 85.7% and 85.3% amino acid (aa) sequence identity with mouse and rat PLCB2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Phospholipase C beta 2

Target: Phospholipase C beta 2 (PLCb2) (phospholipase C beta 2 (PLCb2))

Alternative Name: PLCB2

Background:

Background: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene. The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.

Gene Full Name: phospholipase C beta 2

Gene ID: 5330

UniProt: Q00722

Pathways: WNT Signaling, Thyroid Hormone Synthesis, CXCR4-mediated Signaling Events, G-protein mediated Events, Thromboxane A2 Receptor Signaling