Phospholipase C delta 3 antibody (AA 10-702) (Fluoro647)

Catalog No. ABIN8022134

This Rabbit Polyclonal antibody specifically detects Phospholipase C delta 3 in FACS. It exhibits reactivity toward Human.

Quick Overview for Phospholipase C delta 3 antibody (AA 10-702) (Fluoro647) (ABIN8022134)

Target: Phospholipase C delta 3 (PLCd3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C delta 3 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Phospholipase C delta 3 Antibody (Fluoro647)

Binding Specificity: AA 10-702

Purpose: Anti-PLCD3 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLCD3 recombinant protein (Position: R10-Q702).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Phospholipase C delta 3

Target: Phospholipase C delta 3 (PLCd3)

Alternative Name: PLCD3

Background:

Background: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 is an enzyme that in humans is encoded by the PLCD3 gene. This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.

Gene Full Name: phospholipase C delta 3

Gene ID: 113026

UniProt: Q8N3E9

Pathways: WNT Signaling