Phospholipase C beta 1 antibody (AA 9-834) (Fluoro488)

Catalog No. ABIN8022149

This Rabbit Polyclonal antibody specifically detects Phospholipase C beta 1 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Phospholipase C beta 1 antibody (AA 9-834) (Fluoro488) (ABIN8022149)

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C beta 1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Phospholipase C beta 1 Antibody (Fluoro488)

Binding Specificity: AA 9-834

Purpose: Anti-PLCB1 Antibody Fluoro488 Conjugated

Predicted Reactivity: Human PLCB1 shares 98.8%,98.5% amino acid (aa) sequence identity with mouse,rat PLCB1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLCB1 recombinant protein (Position: H9-D834). Human PLCB1 shares 98.8% and 98.5% amino acid (aa) sequence identity with mouse and rat PLCB1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Phospholipase C beta 1

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Alternative Name: PLCB1

Background:

Background: PLCB1 is also known as PLC-I, EIEE12 or PLC154. The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: phospholipase C beta 1

Gene ID: 23236

UniProt: Q9NQ66

Pathways: WNT Signaling, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events