PYGM antibody (AA 390-804) (PE)

Catalog No. ABIN8022442

The PE-conjugated Rabbit Polyclonal anti-PYGM antibody (ABIN8022442) specifically detects PYGM in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PYGM antibody (AA 390-804) (PE) (ABIN8022442)

Target: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYGM antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-PYGM Antibody (PE)

Binding Specificity: AA 390-804

Purpose: Anti-PYGM Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PYGMshares 95.9%,94.2% amino acid (aa) sequence identity with mouse,rat PYGM,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PYGM recombinant protein (Position: V390-R804). Human PYGMshares 95.9% and 94.2% amino acid (aa) sequence identity with mouse and rat PYGM, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PYGM

Target: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Alternative Name: PYGM

Background:

Background: This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants.

Gene Full Name: glycogen phosphorylase, muscle associated

Gene ID: 5837

UniProt: P11217

Pathways: Cellular Glucan Metabolic Process