PLG antibody (AA 98-356) (Biotin)

Catalog No. ABIN8022835

The Biotin-conjugated Rabbit Polyclonal anti-PLG antibody (ABIN8022835) specifically detects PLG in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PLG antibody (AA 98-356) (Biotin) (ABIN8022835)

Target: PLG (Plasminogen (PLG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLG antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PLG Antibody (Biotin)

Binding Specificity: AA 98-356

Purpose: Anti-Plasminogen/PLG Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Plasminogen/PLG recombinant protein (Position: V98-P356).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLG

Target: PLG (Plasminogen (PLG))

Alternative Name: PLG

Background:

Background: Plasmin is an important enzyme present in blood that degrades many blood plasma proteins, including fibrin clots. It is mapped to 6q26. The degradation of fibrin is termed fibrinolysis. In humans, the plasmin protein is encoded by the PLG gene. The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: plasminogen

Gene ID: 5340

UniProt: P00747

Pathways: Complement System, Lipid Metabolism