Plastin 3 antibody (AA 1-580) (Fluoro647)

Catalog No. ABIN8022998

This Rabbit Polyclonal antibody specifically detects Plastin 3 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Plastin 3 antibody (AA 1-580) (Fluoro647) (ABIN8022998)

Target: Plastin 3 (PLS3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plastin 3 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Plastin 3 Antibody (Fluoro647)

Binding Specificity: AA 1-580

Purpose: Anti-PLS3 Antibody Fluoro647 Conjugated

Predicted Reactivity: Human PLS3 shares 99%,97.9% amino acid (aa) sequence identity with mouse,rat PLS3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLS3 recombinant protein (Position: M1-D580). Human PLS3 shares 99% and 97.9% amino acid (aa) sequence identity with mouse and rat PLS3, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Plastin 3

Target: Plastin 3 (PLS3)

Alternative Name: PLS3

Background:

Background: Plastin-3 is a highly conserved protein that in humans is encoded by the PLS3 gene on the X chromosome. Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83 % identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.

Gene Full Name: plastin 3

Gene ID: 5358

UniProt: P13797