PF4 antibody (AA 30-105) (Fluoro647)

Catalog No. ABIN8023098

The Rabbit Polyclonal anti-PF4 antibody is suitable to detect PF4 in samples from Mouse. It has been validated for FACS.

Quick Overview for PF4 antibody (AA 30-105) (Fluoro647) (ABIN8023098)

Target: PF4 (Platelet Factor 4 (PF4))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PF4 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-PF4 Antibody (Fluoro647)

Binding Specificity: AA 30-105

Purpose: Anti-PF4 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived mouse PF4 recombinant protein (Position: V30-S105). Mouse PF4 shares 74.3%,86.8% amino acid (aa) sequence identity with human,rat PF4,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse PF4 recombinant protein (Position: V30-S105). Mouse PF4 shares 74.3% and 86.8% amino acid (aa) sequence identity with human and rat PF4, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PF4

Target: PF4 (Platelet Factor 4 (PF4))

Alternative Name: Pf4

Background:

Background: Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

Gene Full Name: platelet factor 4

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Gene ID: 56744

UniProt: Q9Z126