PF4 antibody (C-Term) (Fluoro550)

Catalog No. ABIN8023114

The Fluoro550-conjugated Rabbit Polyclonal anti-PF4 antibody (ABIN8023114) specifically detects PF4 in FACS. The antibody is reactive with Human samples.

Quick Overview for PF4 antibody (C-Term) (Fluoro550) (ABIN8023114)

Target: PF4 (Platelet Factor 4 (PF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PF4 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-PF4 Antibody (Fluoro550)

Binding Specificity: C-Term

Purpose: Anti-Platelet factor 4 PF4 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PF4.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PF4

Target: PF4 (Platelet Factor 4 (PF4))

Alternative Name: PF4

Background:

Background: CXCL4, Chemokine (C-X-C motif) ligand 4, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. CXCL4 belongs to the CXC chemokine family. The CXCL4 gene contains 3 exons spanning approximately 1 kb. The gene is encoded on a 10-kb EcoRI fragment of genomic DNA. By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

Gene Full Name: platelet factor 4

Sequence Similarities: Belongs to the intercrine alpha (chemokine CxC) family.

Gene ID: 5196

UniProt: P02776