PRAM1 antibody (AA 361-670) (HRP)

Catalog No. ABIN8023508

This Rabbit Polyclonal antibody specifically detects PRAM1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for PRAM1 antibody (AA 361-670) (HRP) (ABIN8023508)

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRAM1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PRAM1 Antibody (HRP)

Binding Specificity: AA 361-670

Purpose: Anti-PRAM1 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PRAM1 recombinant protein (Position: E361-R670).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PRAM1

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Alternative Name: PRAM1

Background:

Background: PML-RARA-regulated adapter molecule 1 is a protein that in humans is encoded by the PRAM1 gene. The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).

Gene Full Name: PML-RARA regulated adaptor molecule 1

Gene ID: 84106

UniProt: Q96QH2

Pathways: Regulation of Leukocyte Mediated Immunity