POU6F2 antibody (AA 24-446) (Fluoro594)

Catalog No. ABIN8024877

The Rabbit Polyclonal anti-POU6F2 antibody is suitable to detect POU6F2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for POU6F2 antibody (AA 24-446) (Fluoro594) (ABIN8024877)

Target: POU6F2 (POU Class 6 Homeobox 2 (POU6F2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU6F2 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-POU6F2 Antibody (Fluoro594)

Binding Specificity: AA 24-446

Purpose: Anti-POU6F2 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human POU6F2 shares 89.7% amino acid (aa) sequence identity with mouse POU6F2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human POU6F2 recombinant protein (Position: E24-Q446). Human POU6F2 shares 89.7% amino acid (aa) sequence identity with mouse POU6F2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for POU6F2

Target: POU6F2 (POU Class 6 Homeobox 2 (POU6F2))

Alternative Name: POU6F2

Background:

Background: This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Full Name: POU class 6 homeobox 2

Gene ID: 11281

UniProt: P78424