PCOLCE antibody (AA 162-449) (Fluoro647)

Catalog No. ABIN8025383

This Rabbit Polyclonal antibody specifically detects PCOLCE in FACS. It exhibits reactivity toward Human.

Quick Overview for PCOLCE antibody (AA 162-449) (Fluoro647) (ABIN8025383)

Target: PCOLCE (Procollagen C-Endopeptidase Enhancer (PCOLCE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCOLCE antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-PCOLCE Antibody (Fluoro647)

Binding Specificity: AA 162-449

Purpose: Anti-PCOLCE Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PCOLCE shares 75.6%,76.3% amino acid (aa) sequence identity with mouse,rat PCOLCE,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCOLCE recombinant protein (Position: R162-D449). Human PCOLCE shares 75.6% and 76.3% amino acid (aa) sequence identity with mouse and rat PCOLCE, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PCOLCE

Target: PCOLCE (Procollagen C-Endopeptidase Enhancer (PCOLCE))

Alternative Name: PCOLCE

Background:

Background: Procollagen C-endopeptidase enhancer 1 is an enzyme that in humans is encoded by the PCOLCE gene. Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.

Gene Full Name: procollagen C-endopeptidase enhancer

Gene ID: 5118

UniProt: Q15113