PLOD1 antibody (AA 23-640) (Biotin)

Catalog No. ABIN8025385

The Biotin-conjugated Rabbit Polyclonal anti-PLOD1 antibody (ABIN8025385) specifically detects PLOD1 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for PLOD1 antibody (AA 23-640) (Biotin) (ABIN8025385)

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLOD1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PLOD1 Antibody (Biotin)

Binding Specificity: AA 23-640

Purpose: Anti-PLOD1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLOD1 recombinant protein (Position: K23-A640).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLOD1

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Alternative Name: PLOD1

Background:

Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

Gene ID: 5351

UniProt: Q02809