PDCD4 antibody (Middle Region) (HRP)

Catalog No. ABIN8025590

This Rabbit Polyclonal antibody specifically detects PDCD4 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for PDCD4 antibody (Middle Region) (HRP) (ABIN8025590)

Target: PDCD4 (Programmed Cell Death 4 (PDCD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PDCD4 Antibody (HRP)

Binding Specificity: Middle Region

Purpose: Anti-PDCD4 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region human PDCD4, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PDCD4

Target: PDCD4 (Programmed Cell Death 4 (PDCD4))

Alternative Name: PDCD4

Background:

Background: Programmed cell death protein 4 (PDCD4) is a protein that in humans is encoded by the PDCD4 gene. It is mapped to 10q25.2. This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. It also encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined.

Gene Full Name: programmed cell death 4

Gene ID: 27250

UniProt: Q53EL6