PREB antibody (AA 42-236) (Biotin)

Catalog No. ABIN8025783

The Rabbit Polyclonal anti-PREB antibody is suitable to detect PREB in samples from Human. It has been validated for WB, IHC and ELISA.

Quick Overview for PREB antibody (AA 42-236) (Biotin) (ABIN8025783)

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREB antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PREB Antibody (Biotin)

Binding Specificity: AA 42-236

Purpose: Anti-PREB Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human PREB recombinant protein (Position: K42-N236). Human PREB shares 87.7% amino acid (aa) sequence identity with both mouse,rat PREB.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human PREB recombinant protein (Position: K42-N236). Human PREB shares 87.7% amino acid (aa) sequence identity with both mouse and rat PREB.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PREB

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Alternative Name: PREB

Background:

Background: Prolactin regulatory element-binding protein is a protein that in humans is encoded by the PREB gene. This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.

Gene Full Name: prolactin regulatory element binding

Gene ID: 10113

UniProt: Q9HCU5

Pathways: ER-Nucleus Signaling