PRODH antibody (AA 116-433) (HRP)

Catalog No. ABIN8025855

The Rabbit Polyclonal anti-PRODH antibody is suitable to detect PRODH in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for PRODH antibody (AA 116-433) (HRP) (ABIN8025855)

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRODH antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PRODH Antibody (HRP)

Binding Specificity: AA 116-433

Purpose: Anti-PRODH Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PRODH recombinant protein (Position: H116-E433).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PRODH

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Alternative Name: PRODH

Background:

Background: Proline dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the PRODH gene. This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: proline dehydrogenase 1

Gene ID: 5625

UniProt: O43272

Pathways: Response to Water Deprivation, Monocarboxylic Acid Catabolic Process