PRODH antibody (AA 116-433)

Catalog No. ABIN8025859

The Rabbit Polyclonal anti-PRODH antibody (ABIN8025859) specifically detects PRODH in WB, ELISA, IHC and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PRODH antibody (AA 116-433) (ABIN8025859)

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRODH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-PRODH Antibody

Binding Specificity: AA 116-433

Purpose: Anti-PRODH Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PRODH Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PRODH recombinant protein (Position: H116-E433).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PRODH

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Alternative Name: PRODH

Background:

Background: Proline dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the PRODH gene. This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: proline dehydrogenase 1

Molecular Weight: 69 kDa

Gene ID: 5625

UniProt: O43272

Pathways: Response to Water Deprivation, Monocarboxylic Acid Catabolic Process