PCCB antibody (AA 83-539) (Biotin)

Catalog No. ABIN8026126

The Biotin-conjugated Rabbit Polyclonal anti-PCCB antibody (ABIN8026126) specifically detects PCCB in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PCCB antibody (AA 83-539) (Biotin) (ABIN8026126)

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCB antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PCCB Antibody (Biotin)

Binding Specificity: AA 83-539

Purpose: Anti-PCCB Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCCB recombinant protein (Position: D83-L539).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PCCB

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Alternative Name: PCCB

Background:

Background: The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: propionyl-CoA carboxylase subunit beta

Gene ID: 5096

UniProt: P05166

Pathways: Monocarboxylic Acid Catabolic Process