PSCA antibody (AA 21-95) (Fluoro647)

Catalog No. ABIN8026478

This Rabbit Polyclonal antibody specifically detects PSCA in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PSCA antibody (AA 21-95) (Fluoro647) (ABIN8026478)

Target: PSCA (Prostate Stem Cell Antigen (PSCA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSCA antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-PSCA Antibody (Fluoro647)

Binding Specificity: AA 21-95

Purpose: Anti-PSCA Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human PSCA shares 66% amino acid (aa) sequence identity with mouse PSCA.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PSCA recombinant protein (Position: L21-S95). Human PSCA shares 66% amino acid (aa) sequence identity with mouse PSCA.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PSCA

Target: PSCA (Prostate Stem Cell Antigen (PSCA))

Alternative Name: PSCA

Background:

Background: PSCA is also known as PRO232. This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals, this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

Gene Full Name: prostate stem cell antigen

Sequence Similarities: Contains 1 UPAR/Ly6 domain.

Gene ID: 8000

UniProt: O43653