PRSS8 antibody (AA 59-322) (HRP)

Catalog No. ABIN8026553

This Rabbit Polyclonal antibody specifically detects PRSS8 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for PRSS8 antibody (AA 59-322) (HRP) (ABIN8026553)

Target: PRSS8 (Protease, serine, 8 (PRSS8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS8 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PRSS8 Antibody (HRP)

Binding Specificity: AA 59-322

Purpose: Anti-PRSS8 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PRSS8 recombinant protein (Position: Q59-R322).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PRSS8

Target: PRSS8 (Protease, serine, 8 (PRSS8))

Alternative Name: PRSS8

Background:

Background: Prostasin is a protein that in humans is encoded by the PRSS8 gene This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation.

Gene Full Name: serine protease 8

Gene ID: 5652

UniProt: Q16651