PRSS8 antibody (AA 59-322) (PE)

Catalog No. ABIN8026555

The PE-conjugated Rabbit Polyclonal anti-PRSS8 antibody (ABIN8026555) specifically detects PRSS8 in FACS. The antibody is reactive with Human samples.

Quick Overview for PRSS8 antibody (AA 59-322) (PE) (ABIN8026555)

Target: PRSS8 (Protease, serine, 8 (PRSS8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS8 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-PRSS8 Antibody (PE)

Binding Specificity: AA 59-322

Purpose: Anti-PRSS8 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PRSS8 recombinant protein (Position: Q59-R322).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PRSS8

Target: PRSS8 (Protease, serine, 8 (PRSS8))

Alternative Name: PRSS8

Background:

Background: Prostasin is a protein that in humans is encoded by the PRSS8 gene This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation.

Gene Full Name: serine protease 8

Gene ID: 5652

UniProt: Q16651