PSMA6 antibody (AA 1-246) (PE)

Catalog No. ABIN8026965

The Rabbit Polyclonal anti-PSMA6 antibody is suitable to detect PSMA6 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for PSMA6 antibody (AA 1-246) (PE) (ABIN8026965)

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA6 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-PSMA6 Antibody (PE)

Binding Specificity: AA 1-246

Purpose: Anti-PSMA6 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PSMA6 shares 99.6%,100% amino acid (aa) sequence identity with mouse,rat PSMA6,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PSMA6 recombinant protein (Position: M1-D246). Human PSMA6 shares 99.6% and 100% amino acid (aa) sequence identity with mouse and rat PSMA6, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PSMA6

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Alternative Name: PSMA6

Background:

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.

Gene Full Name: proteasome 20S subunit alpha 6

Gene ID: 5687

UniProt: P60900

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA