PRMT6 antibody (AA 45-348) (FITC)

Catalog No. ABIN8027118

The Rabbit Polyclonal anti-PRMT6 antibody is suitable to detect PRMT6 in samples from Human. It has been validated for FACS.

Quick Overview for PRMT6 antibody (AA 45-348) (FITC) (ABIN8027118)

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT6 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-PRMT6 Antibody (FITC)

Binding Specificity: AA 45-348

Purpose: Anti-PRMT6 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PRMT6 recombinant protein (Position: Q45-D348).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PRMT6

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Alternative Name: PRMT6

Background:

Background: Protein arginine N-methyltransferase 6 is an enzyme that in humans is encoded by the PRMT6 gene. The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

Gene Full Name: protein arginine methyltransferase 6

Gene ID: 55170

UniProt: Q96LA8