PROCR antibody (AA 18-210) (APC)

Catalog No. ABIN8027175

The Rabbit Polyclonal anti-PROCR antibody is suitable to detect PROCR in samples from Human. It has been validated for FACS.

Quick Overview for PROCR antibody (AA 18-210) (APC) (ABIN8027175)

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROCR antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-PROCR Antibody (APC)

Binding Specificity: AA 18-210

Purpose: Anti-EPCR/CD201/PROCR Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human EPCR,CD201 recombinant protein (Position: S18-S210). Human EPCR,CD201 shares 65.5%,65.6% amino acid (aa) sequence identity with mouse,rat EPCR,CD201,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human EPCR/CD201 recombinant protein (Position: S18-S210). Human EPCR/CD201 shares 65.5% and 65.6% amino acid (aa) sequence identity with mouse and rat EPCR/CD201, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PROCR

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Alternative Name: PROCR

Background:

Background: Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor), is a protein that in humans is encoded by the PROCR gene. It has also recently been designated CD201 (cluster of differentiation 201). The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. And it is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.

Gene Full Name: protein C receptor

Gene ID: 10544

UniProt: Q9UNN8