PROCR antibody (AA 18-210)

Catalog No. ABIN8027178

The Rabbit Polyclonal anti-PROCR antibody is suitable to detect PROCR in samples from Human. It has been validated for WB and ELISA.

Quick Overview for PROCR antibody (AA 18-210) (ABIN8027178)

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROCR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-PROCR Antibody

Binding Specificity: AA 18-210

Purpose: Anti-EPCR/CD201/PROCR Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human EPCR,CD201 recombinant protein (Position: S18-S210). Human EPCR,CD201 shares 65.5%,65.6% amino acid (aa) sequence identity with mouse,rat EPCR,CD201,respectively.

Characteristics: Anti-EPCR/CD201/PROCR Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human EPCR/CD201 recombinant protein (Position: S18-S210). Human EPCR/CD201 shares 65.5% and 65.6% amino acid (aa) sequence identity with mouse and rat EPCR/CD201, respectively.

Isotype: IgG

Application Details

Application Notes: ELISA, 0.1-0.5 μg/mL, -Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PROCR

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Alternative Name: PROCR

Background:

Background: Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor), is a protein that in humans is encoded by the PROCR gene. It has also recently been designated CD201 (cluster of differentiation 201). The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. And it is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.

Gene Full Name: protein C receptor

Molecular Weight: 46 kDa, 52 kDa

Gene ID: 10544

UniProt: Q9UNN8