PDIA5 antibody (AA 46-481) (Biotin)

Catalog No. ABIN8027179

The Biotin-conjugated Rabbit Polyclonal anti-PDIA5 antibody (ABIN8027179) specifically detects PDIA5 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PDIA5 antibody (AA 46-481) (Biotin) (ABIN8027179)

Target: PDIA5 (Protein Disulfide Isomerase Associated 5 (PDIA5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDIA5 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PDIA5 Antibody (Biotin)

Binding Specificity: AA 46-481

Purpose: Anti-PDIA5 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PDIA5 recombinant protein (Position: R46-Y481).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PDIA5

Target: PDIA5 (Protein Disulfide Isomerase Associated 5 (PDIA5))

Alternative Name: PDIA5

Background:

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants.

Gene Full Name: protein disulfide isomerase family A member 5

Gene ID: 10954

UniProt: Q14554

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis