PDIA6 antibody (AA 20-440)

Catalog No. ABIN8027266

The Mouse Monoclonal anti-PDIA6 antibody (Clone 3H5E7) (ABIN8027266) specifically detects PDIA6 in WB, IHC, FACS, IF and ICC. The antibody is reactive with Human and Monkey samples.

Quick Overview for PDIA6 antibody (AA 20-440) (ABIN8027266)

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDIA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Clone: 3H5E7

Product Details anti-PDIA6 Antibody

Binding Specificity: AA 20-440

Purpose: Anti-PDIA6 Antibody (monoclonal, 3H5E7)

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PDIA6 Antibody.(monoclonal, 3H5E7)-1. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PDIA6 recombinant protein (Position: L20-L440).

Isotype: IgG2b

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Monkey Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PDIA6

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Alternative Name: PDIA6

Background:

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: protein disulfide isomerase family A member 6

Molecular Weight: 48 kDa

Gene ID: 10130

UniProt: Q15084

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis