POMGNT1 antibody (AA 96-394) (Fluoro488)

Catalog No. ABIN8027757

The Rabbit Polyclonal anti-POMGNT1 antibody is suitable to detect POMGNT1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for POMGNT1 antibody (AA 96-394) (Fluoro488) (ABIN8027757)

Target: POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POMGNT1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-POMGNT1 Antibody (Fluoro488)

Binding Specificity: AA 96-394

Purpose: Anti-POMGNT1 Antibody Fluoro488 Conjugated

Predicted Reactivity: Human POMGNT1 shares 99.7% amino acid (aa) sequence identity with both mouse,rat POMGNT1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human POMGNT1 recombinant protein (Position: R96-E394). Human POMGNT1 shares 99.7% amino acid (aa) sequence identity with both mouse and rat POMGNT1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for POMGNT1

Target: POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))

Alternative Name: POMGNT1

Background:

Background: Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 is an enzyme that in humans is encoded by the POMGNT1 gene. This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described.

Gene Full Name: protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)

Gene ID: 55624

UniProt: Q8WZA1