PROS1 antibody (AA 291-676) (HRP)

Catalog No. ABIN8028291

The Rabbit Polyclonal anti-PROS1 antibody is suitable to detect PROS1 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for PROS1 antibody (AA 291-676) (HRP) (ABIN8028291)

Target: PROS1 (PROS) (Protein S (PROS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROS1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PROS1 Antibody (HRP)

Binding Specificity: AA 291-676

Purpose: Anti-Protein S/PROS1 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Protein S recombinant protein (Position: L291-S676).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PROS1

Target: PROS1 (PROS) (Protein S (PROS))

Alternative Name: PROS1

Background:

Background: This PROS1 gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Gene Full Name: protein S

Gene ID: 5627

UniProt: P07225