POMT1 antibody (AA 224-747) (Biotin)

Catalog No. ABIN8028582

The Rabbit Polyclonal anti-POMT1 antibody is suitable to detect POMT1 in samples from Human and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for POMT1 antibody (AA 224-747) (Biotin) (ABIN8028582)

Target: POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POMT1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-POMT1 Antibody (Biotin)

Binding Specificity: AA 224-747

Purpose: Anti-POMT1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human POMT1 shares 81.1%,80.9% amino acid (aa) sequence identity with mouse,rat POMT1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human POMT1 recombinant protein (Position: H224-H747). Human POMT1 shares 81.1% and 80.9% amino acid (aa) sequence identity with mouse and rat POMT1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for POMT1

Target: POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))

Alternative Name: POMT1

Background:

Background: Protein O-mannosyl-transferase 1 is an enzyme that in humans is encoded by the POMT1 gene. The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: protein O-mannosyltransferase 1

Gene ID: 10585

UniProt: Q9Y6A1