PCDHA12 antibody (AA 219-365) (HRP)

Catalog No. ABIN8028676

The HRP-conjugated Rabbit Polyclonal anti-PCDHA12 antibody (ABIN8028676) specifically detects PCDHA12 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for PCDHA12 antibody (AA 219-365) (HRP) (ABIN8028676)

Target: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHA12 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PCDHA12 Antibody (HRP)

Binding Specificity: AA 219-365

Purpose: Anti-PCDHA12 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCDHA12 recombinant protein (Position: K219-V365).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PCDHA12

Target: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Alternative Name: PCDHA12

Background:

Background: Protocadherin alpha-12 is a protein that in humans is encoded by the PCDHA12 gene. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Gene Full Name: protocadherin alpha 12

Gene ID: 56137

UniProt: Q9UN75