PCDHa8 antibody (AA 118-801) (PE)

Catalog No. ABIN8028722

This Rabbit Polyclonal antibody specifically detects PCDHa8 in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for PCDHa8 antibody (AA 118-801) (PE) (ABIN8028722)

Target: PCDHa8 (Protocadherin alpha 8 (PCDHa8))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHa8 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-PCDHa8 Antibody (PE)

Binding Specificity: AA 118-801

Purpose: Anti-PCDHA8 Antibody PE Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCDHA8 recombinant protein (Position: H118-Q801).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PCDHa8

Target: PCDHa8 (Protocadherin alpha 8 (PCDHa8))

Alternative Name: PCDHA8

Background:

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Gene Full Name: protocadherin alpha 8

Gene ID: 56140

UniProt: Q9Y5H6