PCDHa8 antibody (AA 118-801)

Catalog No. ABIN8028724

The Rabbit Polyclonal anti-PCDHa8 antibody (ABIN8028724) specifically detects PCDHa8 in WB, ELISA and FACS. The antibody is reactive with Human and Rat samples.

Quick Overview for PCDHa8 antibody (AA 118-801) (ABIN8028724)

Target: PCDHa8 (Protocadherin alpha 8 (PCDHa8))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHa8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-PCDHa8 Antibody

Binding Specificity: AA 118-801

Purpose: Anti-PCDHA8 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-PCDHA8 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCDHA8 recombinant protein (Position: H118-Q801).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PCDHa8

Target: PCDHa8 (Protocadherin alpha 8 (PCDHa8))

Alternative Name: PCDHA8

Background:

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Gene Full Name: protocadherin alpha 8

Molecular Weight: 150 kDa

Gene ID: 56140

UniProt: Q9Y5H6